Viral loads in clinical specimens and SARS manifestations.
Identifieur interne : 002977 ( Main/Exploration ); précédent : 002976; suivant : 002978Viral loads in clinical specimens and SARS manifestations.
Auteurs : I F N. Hung [République populaire de Chine] ; S K P. Lau ; P C Y. Woo ; K Y YuenSource :
- Hong Kong medical journal = Xianggang yi xue za zhi [ 1024-2708 ] ; 2009.
Descripteurs français
- KwdFr :
- ARN viral (métabolisme), Antiviraux (administration et posologie), Antiviraux (usage thérapeutique), Charge virale, Excrétion virale (), Facteurs temps, Flambées de maladies, Humains, Partie nasale du pharynx (virologie), Pronostic, RT-PCR, Syndrome respiratoire aigu sévère (physiopathologie), Syndrome respiratoire aigu sévère (traitement médicamenteux), Syndrome respiratoire aigu sévère (virologie), Virus du SRAS (isolement et purification), Études rétrospectives.
- MESH :
- administration et posologie : Antiviraux.
- isolement et purification : Virus du SRAS.
- métabolisme : ARN viral.
- physiopathologie : Syndrome respiratoire aigu sévère.
- traitement médicamenteux : Syndrome respiratoire aigu sévère.
- usage thérapeutique : Antiviraux.
- virologie : Partie nasale du pharynx, Syndrome respiratoire aigu sévère.
- Charge virale, Excrétion virale, Facteurs temps, Flambées de maladies, Humains, Pronostic, RT-PCR, Études rétrospectives.
English descriptors
- KwdEn :
- Antiviral Agents (administration & dosage), Antiviral Agents (therapeutic use), Disease Outbreaks, Humans, Nasopharynx (virology), Prognosis, RNA, Viral (metabolism), Retrospective Studies, Reverse Transcriptase Polymerase Chain Reaction, SARS Virus (isolation & purification), Severe Acute Respiratory Syndrome (drug therapy), Severe Acute Respiratory Syndrome (physiopathology), Severe Acute Respiratory Syndrome (virology), Time Factors, Viral Load, Virus Shedding (drug effects).
- MESH :
- chemical , administration & dosage : Antiviral Agents.
- chemical , metabolism : RNA, Viral.
- chemical , therapeutic use : Antiviral Agents.
- drug effects : Virus Shedding.
- drug therapy : Severe Acute Respiratory Syndrome.
- isolation & purification : SARS Virus.
- physiopathology : Severe Acute Respiratory Syndrome.
- virology : Nasopharynx, Severe Acute Respiratory Syndrome.
- Disease Outbreaks, Humans, Prognosis, Retrospective Studies, Reverse Transcriptase Polymerase Chain Reaction, Time Factors, Viral Load.
Abstract
1. A high viral load in nasopharyngeal aspirate (with or without a high viral load in serum) is a useful prognostic indicator of respiratory failure or mortality. The presence of viral RNA in multiple body sites is also indicative of poor prognosis. 2. Early treatment with an effective antiviral agent before day 10 may decrease the peak viral load, and thus ameliorate the clinical symptoms and mortality, and reduce viral shedding and the risk of transmission
PubMed: 20393220
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: 001709
- to stream PubMed, to step Curation: 001709
- to stream PubMed, to step Checkpoint: 001741
- to stream Ncbi, to step Merge: 002120
- to stream Ncbi, to step Curation: 002120
- to stream Ncbi, to step Checkpoint: 002120
- to stream Main, to step Merge: 002A18
- to stream Main, to step Curation: 002977
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Viral loads in clinical specimens and SARS manifestations.</title><author><name sortKey="Hung, I F N" sort="Hung, I F N" uniqKey="Hung I" first="I F N" last="Hung">I F N. Hung</name><affiliation wicri:level="1"><nlm:affiliation>Department of Microbiology, The University of Hong Kong, Queen Mary Hospital Compound, Pokfulam Road, Hong Kong SAR, China. ivanhung@hku.hk</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Microbiology, The University of Hong Kong, Queen Mary Hospital Compound, Pokfulam Road, Hong Kong SAR</wicri:regionArea><wicri:noRegion>Hong Kong SAR</wicri:noRegion></affiliation></author><author><name sortKey="Lau, S K P" sort="Lau, S K P" uniqKey="Lau S" first="S K P" last="Lau">S K P. Lau</name></author><author><name sortKey="Woo, P C Y" sort="Woo, P C Y" uniqKey="Woo P" first="P C Y" last="Woo">P C Y. Woo</name></author><author><name sortKey="Yuen, K Y" sort="Yuen, K Y" uniqKey="Yuen K" first="K Y" last="Yuen">K Y Yuen</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2009">2009</date><idno type="RBID">pubmed:20393220</idno><idno type="pmid">20393220</idno><idno type="wicri:Area/PubMed/Corpus">001709</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">001709</idno><idno type="wicri:Area/PubMed/Curation">001709</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">001709</idno><idno type="wicri:Area/PubMed/Checkpoint">001741</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">001741</idno><idno type="wicri:Area/Ncbi/Merge">002120</idno><idno type="wicri:Area/Ncbi/Curation">002120</idno><idno type="wicri:Area/Ncbi/Checkpoint">002120</idno><idno type="wicri:doubleKey">1024-2708:2009:Hung I:viral:loads:in</idno><idno type="wicri:Area/Main/Merge">002A18</idno><idno type="wicri:Area/Main/Curation">002977</idno><idno type="wicri:Area/Main/Exploration">002977</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Viral loads in clinical specimens and SARS manifestations.</title><author><name sortKey="Hung, I F N" sort="Hung, I F N" uniqKey="Hung I" first="I F N" last="Hung">I F N. Hung</name><affiliation wicri:level="1"><nlm:affiliation>Department of Microbiology, The University of Hong Kong, Queen Mary Hospital Compound, Pokfulam Road, Hong Kong SAR, China. ivanhung@hku.hk</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Microbiology, The University of Hong Kong, Queen Mary Hospital Compound, Pokfulam Road, Hong Kong SAR</wicri:regionArea><wicri:noRegion>Hong Kong SAR</wicri:noRegion></affiliation></author><author><name sortKey="Lau, S K P" sort="Lau, S K P" uniqKey="Lau S" first="S K P" last="Lau">S K P. Lau</name></author><author><name sortKey="Woo, P C Y" sort="Woo, P C Y" uniqKey="Woo P" first="P C Y" last="Woo">P C Y. Woo</name></author><author><name sortKey="Yuen, K Y" sort="Yuen, K Y" uniqKey="Yuen K" first="K Y" last="Yuen">K Y Yuen</name></author></analytic><series><title level="j">Hong Kong medical journal = Xianggang yi xue za zhi</title><idno type="ISSN">1024-2708</idno><imprint><date when="2009" type="published">2009</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Antiviral Agents (administration & dosage)</term><term>Antiviral Agents (therapeutic use)</term><term>Disease Outbreaks</term><term>Humans</term><term>Nasopharynx (virology)</term><term>Prognosis</term><term>RNA, Viral (metabolism)</term><term>Retrospective Studies</term><term>Reverse Transcriptase Polymerase Chain Reaction</term><term>SARS Virus (isolation & purification)</term><term>Severe Acute Respiratory Syndrome (drug therapy)</term><term>Severe Acute Respiratory Syndrome (physiopathology)</term><term>Severe Acute Respiratory Syndrome (virology)</term><term>Time Factors</term><term>Viral Load</term><term>Virus Shedding (drug effects)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>ARN viral (métabolisme)</term><term>Antiviraux (administration et posologie)</term><term>Antiviraux (usage thérapeutique)</term><term>Charge virale</term><term>Excrétion virale ()</term><term>Facteurs temps</term><term>Flambées de maladies</term><term>Humains</term><term>Partie nasale du pharynx (virologie)</term><term>Pronostic</term><term>RT-PCR</term><term>Syndrome respiratoire aigu sévère (physiopathologie)</term><term>Syndrome respiratoire aigu sévère (traitement médicamenteux)</term><term>Syndrome respiratoire aigu sévère (virologie)</term><term>Virus du SRAS (isolement et purification)</term><term>Études rétrospectives</term></keywords><keywords scheme="MESH" type="chemical" qualifier="administration & dosage" xml:lang="en"><term>Antiviral Agents</term></keywords><keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>RNA, Viral</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Antiviral Agents</term></keywords><keywords scheme="MESH" qualifier="administration et posologie" xml:lang="fr"><term>Antiviraux</term></keywords><keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Virus Shedding</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Severe Acute Respiratory Syndrome</term></keywords><keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>SARS Virus</term></keywords><keywords scheme="MESH" qualifier="isolement et purification" xml:lang="fr"><term>Virus du SRAS</term></keywords><keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>ARN viral</term></keywords><keywords scheme="MESH" qualifier="physiopathologie" xml:lang="fr"><term>Syndrome respiratoire aigu sévère</term></keywords><keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Severe Acute Respiratory Syndrome</term></keywords><keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Syndrome respiratoire aigu sévère</term></keywords><keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Antiviraux</term></keywords><keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Partie nasale du pharynx</term><term>Syndrome respiratoire aigu sévère</term></keywords><keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Nasopharynx</term><term>Severe Acute Respiratory Syndrome</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Disease Outbreaks</term><term>Humans</term><term>Prognosis</term><term>Retrospective Studies</term><term>Reverse Transcriptase Polymerase Chain Reaction</term><term>Time Factors</term><term>Viral Load</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Charge virale</term><term>Excrétion virale</term><term>Facteurs temps</term><term>Flambées de maladies</term><term>Humains</term><term>Pronostic</term><term>RT-PCR</term><term>Études rétrospectives</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">1. A high viral load in nasopharyngeal aspirate (with or without a high viral load in serum) is a useful prognostic indicator of respiratory failure or mortality. The presence of viral RNA in multiple body sites is also indicative of poor prognosis. 2. Early treatment with an effective antiviral agent before day 10 may decrease the peak viral load, and thus ameliorate the clinical symptoms and mortality, and reduce viral shedding and the risk of transmission</div></front></TEI><affiliations><list><country><li>République populaire de Chine</li></country></list><tree><noCountry><name sortKey="Lau, S K P" sort="Lau, S K P" uniqKey="Lau S" first="S K P" last="Lau">S K P. Lau</name><name sortKey="Woo, P C Y" sort="Woo, P C Y" uniqKey="Woo P" first="P C Y" last="Woo">P C Y. Woo</name><name sortKey="Yuen, K Y" sort="Yuen, K Y" uniqKey="Yuen K" first="K Y" last="Yuen">K Y Yuen</name></noCountry><country name="République populaire de Chine"><noRegion><name sortKey="Hung, I F N" sort="Hung, I F N" uniqKey="Hung I" first="I F N" last="Hung">I F N. Hung</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/SrasV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002977 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 002977 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= SrasV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= pubmed:20393220
|texte= Viral loads in clinical specimens and SARS manifestations.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:20393220" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a SrasV1
| This area was generated with Dilib version V0.6.33. |  |